Clinical evidence for what you sip.

Every compound in a Karha blend is backed by peer-reviewed research. We publish our assay results, link to primary sources, and maintain a living formulary that grows with the evidence.

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Clinical Studies
CompoundHerbTrial DesignOutcomeCitation
Withanolide AAshwagandhaRCT n=60 300 mg 60 dSerum cortisol −27 % (p<0.01)Salve et al. 2019
Bacoside ABrahmiRCT n=46 300 mg 12 wWorking memory +18 % (p<0.01)Stough et al. 2008
CurcuminTurmericRCT n=120 1 g+piperine 8 wCRP −48 %, IL-6 −22 %Hewlings & Kalman 2017
GlycyrrhizinLicoriceMeta (4 RCTs) 380 mg 6 wPeptic ulcer healing +31 %Wang et al. 2015
CrocinSaffronRCT n=40 30 mg 6 wHAM-D −43 % (SSRI-comparable)Modabbernia et al. 2014
Gallic acidTriphalaRCT n=34 500 mg 12 wGut transit −28 %, pH normalizedPeterson et al. 2017
EugenolTulsiRCT n=150 300 mg 4 wSalivary IgA +19 %Jamshidi & Cohen 2017
AsiaticosideGotu KolaRCT n=28 500 mg 8 wAcoustic startle ↓ 50 %Bradwejn et al. 2000
Assay & Quality Protocol

Six steps from raw herb to batch release

  1. 1Raw material identity (TLC + HPTLC)
  2. 2Heavy-metal screen (ICP-MS <0.5 ppm)
  3. 3Microbial limits (USP <61>)
  4. 4Active-compound assay (HPLC calibrated)
  5. 5Stability test (40 °C / 75 % RH, 6-month)
  6. 6Batch release COA published
Lab assay photo
Sample Certificate of Analysis
BatchKAR-NID-2604
CompoundWithanolide A
Assay Result≥ 4.2 mg/g
HPLC VerifiedBatch Released
Research Partners
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IIT Bombay

Department of Chemistry — phytochemical fingerprinting and compound isolation partnerships since 2019.

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CSIR-CDRI Lucknow

Central Drug Research Institute — bioavailability studies and pharmacokinetic modelling.

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National Institute of Ayurveda, Jaipur

Clinical trial design and traditional-knowledge documentation under the TKDL framework.

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Arya Vaidya Sala, Kottakkal

Kerala’s foremost Ayurvedic institution — formulation peer review and raw-material provenance verification.